CLEVELAND - Josh Tomlin pitched into the seventh inning and Carlos Santana drove in three runs with a bases-loaded double, leading the Cleveland Indians to an 8-2 victory over the Boston Red Sox on Friday night.

Tomlin (7-2) made one mistake — a two-run homer by David Ortiz in the fourth — in 6 1/3 innings. The right-hander struck out five and allowed five hits.

Santana's double off Henry Owens (4-4) highlighted a four-run third inning. Chris Johnson added an RBI single, giving Cleveland a 4-0 lead.

Jerry Sands, who hit a solo homer in the seventh, had an RBI double in the fifth when Cleveland scored three times.

Ortiz, who returned to the lineup after not playing in three of the previous six games, belted his 37th home run of the season and 503rd of his career through a 20 mph wind blowing in from right field.

Ortiz was 1 for 3 before leaving for a pinch-hitter in the eighth.