FLORHAM PARK, N.J. — It appears Nick Mangold will have to sit this one out.

The New York Jets centre is doubtful to play Sunday against the Cleveland Browns because of a sprained ankle.

Mangold has missed just four games in his 11-year career, including one in each of the last two seasons. His right ankle was heavily taped on Thursday, and he didn't practice all week.

Wesley Johnson would likely replace Mangold, as he did after the centre was injured early in the first quarter of New York's 24-16 win over Baltimore last Sunday.

"Obviously, it's huge shoes to fill," Johnson said Friday. "I've just got to go out there and try to play my game, and make sure all five of us (linemen) play well, and we play well as an offence and win."

The Jets could be down another starter on Sunday with left tackle Ryan Clady questionable because of an ailing shoulder. He has been playing through the injury for a few weeks but will likely be a game-time decision for coach Todd Bowles.

Bowles said Ben Ijalana would slide over from right tackle to left tackle if Clady can't go. With Brent Qvale doubtful with a neck injury, the Jets are also considering activating Breno Giacomini from the reserve-physically unable to perform list to play right tackle.

Giacomini missed all of training camp with a back injury and returned to practice last week after missing the first six games, per NFL rules for players on reserve-PUP. Giacomini, who started every game the last two seasons for the Jets, recently said he felt ready to play.

"We haven't made a decision on it," Bowles said. "If (Qvale) can't play, we have to wait and see how Clady is feeling."

Wide receiver Devin Smith is also on reserve-PUP and close to returning. He has been out since December, when he tore the anterior cruciate ligament in his right knee.

"He's been running around pretty good," Bowles said.

Defensive end Muhammad Wilkerson is questionable with a sore ankle that kept him out of last week's game. He was limited Thursday and Friday after sitting out Wednesday. Bowles said he will be a game-time decision.

Linebackers Darron Lee (ankle) and Bruce Carter (quadriceps) have already been ruled out for the game. Cornerback Buster Skrine (knee) and tight end Austin Seferian-Jenkins (ankle) are doubtful.

The Jets would use a combination of Marcus Williams and Darryl Roberts at cornerback opposite Darrelle Revis with Skrine unlikely to play.

With Ryan Fitzpatrick back as the starting quarterback after being benched and Geno Smith out for the rest of the season with a torn ACL, the focus turned to the backups.

Bryce Petty, a fourth-rounder last year, has been practicing the last two weeks after injuring his shoulder in the preseason. Christian Hackenberg, a second-rounder this year, is also on the roster and has gotten a lot of snaps during the last few months.

But Bowles refused to announce who the No. 2 quarterback — possibly a few errant tosses by Fitzpatrick away from playing — would be on Sunday.

"It's a matter of me just telling the coaches at this point," Bowles said, before adding: "Both of them are ready to play."

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