FORT MYERS, Fla. - Minnesota Twins pitcher Ervin Santana has been suspended for 80 games by Major League Baseball after testing positive for the performance-enhancing substance Stanozolol.

MLB announced the punishment Friday. This is the third penalty for a positive Stanozolol test reported by MLB in the last eight days, following Seattle pitcher David Rollins and Atlanta pitcher Arodys Vizcaino.

Santana must sit out the first half of the season. This is his first season with the Twins after signing a four-year, $55 million contract. He'll lose $5,901,639 of his $13.5 million salary this season.

Santana said in a statement released by the players' union he "can't pinpoint" how the substance entered his body.

Santana was 14-10 with a 3.95 ERA in 31 starts for the Braves last year.

Over the last five years, Santana averaged 12 wins, 207 innings and 164 strikeouts while making 30 or more starts each season. The Twins pursued him a year ago, but he held out until March and signed with Atlanta for one season and $14.1 million.

Santana was picked for the All-Star game in 2008, his fourth of eight seasons with the Los Angeles Angels, who traded him to the Kansas City Royals for 2013. Because Santana turned down a qualifying offer from the Braves, his signing came with draft-pick compensation. The Twins must forfeit their 2015 second-round selection.