SAN DIEGO -- Phil Hughes threw seven shutout innings and Trevor Plouffee homered in the Minnesota Twins' 2-0 victory over the punchless San Diego Padres on Wednesday night.
Padres starter Tyson Ross (5-4) nearly matched Hughes, allowing one run on three hits over seven innings, walking three and striking out eight.
Chris Parmelee's sacrifice fly to left in the sixth scored Joe Mauer and Plouffee hit his third home run in the eighth.
Glen Perkins pitched a perfect ninth to collect his 14th save in 16 chances.
Hughes (5-1) came over from the Yankees in the off-season, signing a $24 million, three-year deal. He won his fifth straight decision and didn't walk a batter for the fifth consecutive start, while striking out seven.
The Padres have been shut out eight times, tops in the majors.
Ross struck out eight for the third consecutive start, which is one off his season-high.
Mauer walked with one out in the sixth and stole second off Rene Rivera, who threw out three runners attempting to steal in his last start Sunday in Denver. Plouffe then hit a slow chopper to third and beat Chase Headley's throw, with Mauer moving to third.
Mauer scored on Parmelee's sacrifice and Plouffe advanced to third on a throwing error by Headley. Ross then walked Kurt Suzuki, but escaped further damage when Jason Kubel flied out.
Ross breezed through the first five innings, allowing two singles and a walk while striking out six.
Kubel was the only Twin getting into scoring position, advancing to second after walking and stealing second in the second. Kubel was stranded when Danny Santana struck out and Aaron Hicks grounded out.
The Padres looked poised to tie the game in the sixth when Headley and Yonder Alonso singled with no outs. But Jedd Gyorko and Cameron Maybin grounded out and Will Venable struck out.
The Padres, who had hits in each of the first four innings, threatened in the third with two outs when Seth Smith and Headley had consecutive singles. But Alonso, who was elevated to fourth in the order, flied to centre.
Another Padres baserunner reached with two outs when Maybin collected his second hit in the fourth, but Rivera struck out to end the inning.
Smith had three of the Padres' eight hits.
NOTES: Padres manager Bud Black will miss Thursday's game against the Cubs to attend daughter Jessie's graduation from the University of Maryland. Black will return for Friday's game. . OF Carlos Quentin remains sidelined with a groin injury, but will likely avoid the DL. . With 18 doubles, Plouffe is four doubles shy of last year's career high. . Ex-Twins 3B Corey Koskie and area scout John Wilson will represent the team at the first-year player draft on June 5 . Twins RHP Kyle Gibson (4-3, 4.20) faces Giants RHP Tim Lincecum (3-3, 4.74) to open a three-game series on Friday. The Padres send LHP Eric Stults (2-4, 4.50) against Cubs RHP Jake Arrieta (0-0, 2.70) on Thursday.