| Erick Aybar | SS | 5/21/2013 | day-to-day | Left game - right knee soreness |
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| Peter Bourjos | CF | 4/30/2013 | on 15-day DL | Strained left hamstring |
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| Kevin Jepsen | P | 4/13/2013 | on 15-day DL | Right triceps tightness |
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| Jered Weaver | P | 4/8/2013 | on 15-day DL | Fractured left elbow - out 4-6 weeks |
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| Ryan Madson | P | 3/22/2013 | on 15-day DL | Recovery from right elbow surgery |
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| Andrew Taylor | P | 3/22/2013 | on 60-day DL | Left labrum tear |
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