| John Gast | P | 5/25/2013 | day-to-day | Left game - left shoulder tightness |
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| Fernando Salas | P | 5/21/2013 | on 15-day DL | Right shoulder irritation |
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| Jaime Garcia | P | 5/18/2013 | on 15-day DL | Left shoulder strain |
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| Jake Westbrook | P | 5/9/2013 | on 15-day DL | Right elbow inflammation |
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| Rafael Furcal | SS | 3/22/2013 | on 60-day DL | Right elbow surgery - out for season |
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| Jason Motte | P | 3/22/2013 | on 60-day DL | Right elbow surgery - out for season |
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| Chris Carpenter | P | 2/22/2013 | on 60-day DL | Nerve irritation, right shoulder |
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