| Matt Diaz | LF | 5/19/2013 | on 15-day DL | Left knee bone contusion |
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| Chris Valaika | 3B | 5/8/2013 | on 15-day DL | Fractured left wrist |
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| Donovan Solano | 2B | 5/6/2013 | on 15-day DL | Strained left intercostal muscle |
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| Giancarlo Stanton | RF | 4/30/2013 | on 15-day DL | Strained right hamstring |
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| Joe Mahoney | 1B | 4/28/2013 | on 15-day DL | Hamstring strain |
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| Casey Kotchman | 1B | 4/4/2013 | on 60-day DL | Strained left hamstring |
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| Jose Ceda | P | 3/31/2013 | on 60-day DL | Recovery from right elbow surgery |
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| Logan Morrison | LF | 3/31/2013 | on 60-day DL | Recovery from right knee surgery |
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| Alfredo Silverio | LF | 3/31/2013 | on 60-day DL | Sprained right elbow |
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| Henderson Alvarez | P | 3/27/2013 | on 60-day DL | Mild right shoulder inflammation |
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| Nathan Eovaldi | P | 3/24/2013 | on 60-day DL | Mild right shoulder inflammation |
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