Allen Park, MI (Sports Network) - The Detroit Lions placed safety Marquand Manuel on injured reserve due to a shoulder problem, meaning he will miss the remainder of the season.
The team also put cornerback Jack Williams on IR with a torn ACL in his left knee.
Lions safety Kalvin Pearson (hamstring), guard Stephen Peterman (ankle), linebacker Ernie Sims (hamstring), defensive end Dewayne White (toe) and wide receiver Derrick Williams (hip) all didn't practice Wednesday.
The Lions host Cleveland on Sunday in a matchup between a pair of 1-8 teams.
Detroit signed center Melvin Fowler and also inked defensive back DeAngelo Smith from the practice squad on Wednesday.