Hossa scored twice and Kane added a goal and an assist Wednesday as the Chicago Blackhawks overcame an early two-goal deficit to defeat the free-falling Leafs 5-4.
Kane tied the game 3-3 and assisted on Hossa's go-ahead goal as the Blackhawks sent Toronto to its fourth straight regulation loss. The Leafs have just one win in their last 11 games and sit four points adrift in the Eastern Conference playoff race.
"We can't really give up," said Leafs goalie Jonas Gustavsson, who was shaky at times but finished with 30 saves. "I know no one on this team is going to do that."
Hossa's goal late in the second period gave the Blackhawks their first lead at 4-3. He added an empty-net goal with 16 seconds left that turned out to be the game-winner after Toronto's Mike Brown scored with four seconds remaining.
The Leafs were unable to hold on to a 3-1 lead they built late in the first period for embattled coach Ron Wilson.
Toronto, which is an abysmal 1-9-1 since Feb. 7, came out strong a night after fans at Air Canada Centre showered the team with chants of "Fire Wilson!" in the third period of a 5-3 loss to Florida.
"I don't look at it as pressure like what you think," Wilson said. "Pressure is when you're fighting for your life and you've got cancer or something like that. (With) this you're trying to win hockey games.
"We showed up and played, for the most part, a good game."
Wilson said he thought his club deserved a better fate against the Blackhawks.
"Tonight I have no argument with the effort," he said. "When you put in an effort like that more than likely you're going to win. Tonight we didn't."
"We've been talking about how bad our starts have been, and we got the start we wanted, and then let them back into it," Toronto defenceman Luke Schenn said. "A couple goals there that we shouldn't give up, not blaming the goalie, just everyone in general. When you get a lead you've got to clamp down."
Despite the loss, the Leafs players saw encouraging signs.
"Looking back a couple games, I thought this was a step forward, at least how we played the game," defenceman Carl Gunnarsson said. "We did some mistakes in our own end and they took advantage of it, but we had some chances tonight."
The Blackhawks, who came in having lost three in a row and won for only the fifth time in their last 17 contests, have fallen from first in the NHL on Jan. 20 to sixth in the Western Conference. During the slide, Chicago's highly skilled, highly-paid offensive stars -- especially Kane -- often haven't performed up to expectations.
But on Wednesday, both Kane and Hossa battled through traffic and controlled the puck to spark the Blackhawks' comeback.
"I think Kaner had an excellent game," Chicago coach Joel Quenneville said. "I look back over the season and this game stands out as far as puck possession, threat to score off the rush, in-zone, time of possession.
"Offensively and defensively he had a real purpose, liked his leadership as well. Our top guys have got to be, not just our best players, but they have to lead us through this stretch here."
Kane scored for the second straight game, but only for the fifth time in his last 25.
"We'll try to get some wins, get some points and try to finish the season strong," Kane said. "For sure, we're desperate. We're in the back half of the West, so how can you not be."
"Ray did an outstanding job," Quenneville said. "You look back over the year, you get some goalie wins and Ray was instrumental in us winning tonight."
Blackhawks captain and leading goal scorer Jonathan Toews missed his fifth game with an upper-body injury, believed to be a concussion. Defenceman Niklas Hjalmarsson sat out his third straight and 10th in his last 11, with concussion symptoms.
Defenceman Johnny Oduya, acquired by Chicago from Winnipeg just before Monday's trade deadline, played his first game with Chicago.
The Blackhawks went 0-for-2 on the power-play and have scored just one goal in their last 41 chances.
The Maple Leafs led 3-2 after a first period that mirrored the recent play and records of the two teams.
Bozak opened the scoring 59 seconds in from the side of the net with a soft goal when he slipped a backhand shot under Crawford's pads.
Shaw tied it 1-1 with 8:59 left in the first when he drove from the left corner into the slot and beat Gustavsson between the pads. Shaw connected in his first game after being recalled from Rockford of the AHL for the second time this season.
Lupul's power-play tip in just 28 seconds later, set up by Phil Kessel's pinpoint feed, restored the Maple Leafs' lead at 2-1.
MacArthur made it 3-1 with 3:07 left in the first. After Mikhail Grabovski's shot struck the skate of Blackhawks defenceman Brent Seabrook, MacArthur shovelled in the loose puck before Seabrook could find it.
Kruger's deflection of Nick Leddy's shot from the point cut it to 3-2 with 30 seconds remaining in the period.
"It was a huge play and got us back to within one," Kane said. "We had a great second period."
Chicago led 4-3 after two periods thanks to goals by Kane and Hossa on strong efforts.
Kane tied it 3-3 at 8:33 of the second. He pounced on a rebound of Andrew Brunette's shot, plowed into traffic and flipped in a high shot from a sharp angle to Gustavsson's left.
Hossa gave Chicago its first lead at 4-3 just over four minutes later. After driving down the slot and past two Toronto defenders, Hossa fired a shot just inside the left post.
Emery made a tough kick save on Toronto rookie Matt Frattin with 4:30 left in the third to preserve the lead.
NOTES: Blackhawks LW Brandon Bollig appeared in his first NHL game following his recall from Rockford on Tuesday. He fought Schenn. ... Chicago D Steve Montador missed his 11th game with an undisclosed upper-body injury. ... Toronto C Matthew Lombardi was a healthy scratch for the first time this season. He has just one goal and two assists in his last 15 games and is a team-worst minus-13. ... The game was the only one this season between the two Original Six franchises. Toronto and Chicago have not played more than once in season since 2001-02 and over the last nine seasons have met only seven times.