Kyle Quinlan was 15-of-26 passing for 298 yards and three touchdowns Thursday as the defending Vanier Cup champions rolled the York Lions 54-14 in Canadian university football.
Kasean Davis-Reynolds dominated on the ground for No. 1 McMaster, rushing for 169 yards and two TDs on 18 carries.
Andrin Masotti, Brad Fochesato, Tyler Loveday and Josh Vandeweerd caught touchdowns for the Marauders (6-0), while Tyler Crapigna was 3-for-3 on field-goal attempts.
Backup quarterback Marshall Ferguson came on in relief for Quinlan and finished 8-of-14 for 102 yards and a TD.
Lions receiver Jonelle Tolbert was one of the lone bright spots for York (1-5) on the night, catching five passes for 78 yards and two touchdowns. William Austin added four catches for 100 yards.
Elsewhere in the CIS it was: Wilfrid Laurier 12, Waterloo 0; and McGill 34, Bishop's 20.
At Toronto, Lions quarterback Myles Gibbon was 11-of-22 passing for one touchdown and an interception, while backup Dimitar Sevdin was 2-of-6 for 70 yards and a TD.
After Crapigna gave McMaster a 6-0 with two early field goals, Davis-Reynolds rumbled 38 yards to make it 13-0 after one quarter.
Loveday caught a 19-yard pass from Quinlan early in the second before Gibbon found Tolbert from 13 yards out to cut the McMaster lead to 20-7.
But Fochesato and Quinlan hooked up on a 62-yard touchdown late in the quarter as the Marauders led by 20 at the break.
Davis-Reynolds scored on 24-yard run and Masotti found the end zone on a 78-yard pass play after the break as McMaster blew the game wide open to lead 44-7 after three quarters.
Ferguson found Vandeweerd from two yards out late in the fourth before Tolbert capped the scoring with his second TD for the Lions.
Golden Hawks 12, Warriors 0
At Waterloo, Ont., Ronnie Pfeffer kicked four field goals to provide all of the offence as Wilfrid Laurier (3-3) shut out the Warriors (1-5).
Redmen 34, Gaiters 20
At Montreal, Samy Rassy kicked five field goals and Shaquille Johnson caught nine passes for 113 yards and a touchdown as McGill (2-4) got past Bishop's (2-4).