ORCHARD PARK, N.Y. - Buffalo Bills starting offensive guard Chris Williams and backup receiver Marcus Easley have been ruled out from playing against the New England Patriots on Sunday.

Williams, with a back injury, and Easley (left leg) will both miss their third straight games.

Running back Fred Jackson is listed as questionable because of a sore right ankle. Jackson also missed practice Friday because of the flu.

Starting defensive tackle Kyle Williams is listed as questionable. He has practiced all week and has a chance to return after missing one game with a right knee injury.

Starting linebackers Nigel Bradham (left knee) and Brandon Spikes (ribs) and starting safety Aaron Williams (wrist and neck) practiced Friday but are listed as questionable.

The Bills and AFC East rival Patriots both have 3-2 records.