European giants Manchester United and Juventus head into Tuesday's Champions League match at Old Trafford with both sides dealing with a rash of injuries. Among them are United's Alexis Sanchez, who is out with an undisclosed ailment, while the Bianconeri will be without of the services of forward Mario Mandzukic, who is out with a sprained ankle.

Three-time defending champion Real Madrid is in crisis after four defeats in five games as it returns to the Champions League on Tuesday.

Diego Rossi scored two goals and Los Angeles FC tied the Vancouver Whitecaps 2-2 on Sunday to set an MLS record for points in an inaugural season with 57. Vancouver (12-13-8) was eliminated from the playoffs, sitting five points back of sixth-place Real Salt Lake.

Everton substitutes Dominic Calvert-Lewin and Cenk Tosun scored late in a 2-0 win over Crystal Palace on Sunday as the Toffees won their third straight Premier League game.

Serie A leaders Juventus announced on Sunday that midfielder Emre Can would be sidelined as he undergoes tests on a thyroid nodule. The team says that the Germany international could require surgery, but did not give a timetable for Can's treatment. He is unlikely to feature in the team's midweek Champions League clash with Manchester United at Old Trafford.

Lionel Messi has broken a bone in his right arm and will be sidelined for about three weeks. Barcelona made the announcement on Saturday after Messi left their Spanish league match against Sevilla in the first half at Camp Nou Stadium.

Joe Hart endured a tough return to former club Manchester City as Burnley was thrashed 5-0 by the champions in the English Premier League on Saturday.

The Vancouver Whitecaps have one last shot at keeping their playoff hopes alive. The Whitecaps will be in California on Sunday to face off against Los Angeles FC. A Vancouver victory could stave off elimination, at least temporarily. Any other result and the Whitecaps will officially be out of contention.

Cristiano Ronaldo became the first player to net 400 goals across Europe's top five leagues. It wasn't enough on Saturday to maintain Juventus' perfect start to the season.

Without Cristiano Ronaldo for the first time in nearly a decade, Real Madrid reached the worst scoring drought in its history.

Bayern Munich survived a scare at Wolfsburg to end its winless streak with a 3-1 victory, and league leader Borussia Dortmund continued to impress with a 4-0 win at Stuttgart in the Bundesliga on Saturday.

Deflated after seeing his team concede a last-minute goal against his former club, Jose Mourinho looked up from his seat in the dugout to see a rival coach taunting him just a few meters away. So began a chain of events that offered another illustration of why the Manchester United manager remains the biggest box-office draw in English soccer.

LA Galaxy striker Zlatan Ibrahimovic distanced himself from rumours of a potential loan return to former club Manchester United in January, citing his need for rest at age 37. "I think I’m in a situation where I need to have a good balance between work and rest," told Sky Sports.

The agent for the eight-time Olympic gold medallist says that the 32-year-old has turned down a contract offer from Maltese champions, Valletta FC. "Usain does not wish to pursue this Malta opportunity," said Ricky Simms, his agent. "There is a lot of interest in Usain playing football. We regularly receive similar approaches."