Indianapolis, IN (SportsNetwork.com) - Indianapolis Colts linebacker Jerrell Freeman will miss Monday's game against the Eagles with a hamstring injury.

Freeman, who missed practice all week, had started all 33 games with the Colts since he arrived in Indianapolis in 2012. He has 278 tackles, 7 1/2 sacks and three interceptions during his time with the Colts.

Freeman is expected to be replaced by Josh McNary, a second-year player who has never started a game.

Nose tackle Josh Chapman (ankle), center/guard Khaled Holmes (ankle) and defensive tackle Arthur Jones (shoulder) are all listed as questionable. Guard Joe Reitz (ankle) also has been ruled out.