ANAHEIM, Calif. — Chris Davis hit a tiebreaking, two-run homer in the seventh inning — one of four in the game by the Orioles — and Baltimore defeated the Los Angeles Angels 9-4 on Friday night in the series opener after blowing a three-run lead.

Mark Trumbo also hit a two-run blast, and Joey Rickard and Manny Machado added back-to-back solo shots for the AL East leaders who improved to 8-7 away from home. They had played just two road games since April 28 before opening a nine-game West Coast trip in Anaheim.

Angels starter Hector Santiago gave up Baltimore's first three homers before being ejected in the third inning for gesturing to home-plate umpire John Tumpane about how he was calling balls and strikes.

Mychal Givens (3-0) allowed two hits and no runs in 1 1/3 innings. Jose Alvarez (1-2) took the loss.