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 Zenit St. Petersburg (RUS) vs. Torino (ITA) (Zenit advances 2-1 on aggregate)

Date Match-Up Result
 Thursday, March 12 Torino at Zenit St. Petersburg 0-2
  Thursday, March 19 Zenit St. Petersburg at Torino 0-1

 

Bruges (BEL) vs. Besiktas (TUR) (Bruges advances 5-2 on aggregate)

Date Match-Up Result
 Thursday, March 12 Besiktas at Bruges 1-2
 Thursday, March 19 Bruges at Besiktas 3-1

 

Napoli (ITA) vs. Dynamo Moscow (RUS) (Napoli advances 3-1 on aggregate)

Date Match-Up Result
 Thursday, March 12 Dynamo Moscow at Napoli 1-3
 Thursday, March 19  Napoli at Dynamo Moscow 0-0

 

Wolfsburg (GER) vs. Inter Milan (ITA) (Wolfsburg advances 5-2 on aggregate)

Date Match-Up Result
 Thursday, March 12   Inter Milan at Wolfsburg 1-3
  Thursday, March 19   Wolfsburg at Inter Milan 2-1

 

Fiorentina (ITA) vs. Roma (ITA) (Fiorentina advances 4-1 on aggregate)

Date Match-Up Result
Thursday, March 12 Roma at Fiorentina 1-1
 Thursday, March 19   Fiorentina at Roma 3-0

 

Everton (ENG) vs. Dynamo Kyiv (UKR) (Dynamo advances 6-4 on aggregate)

Date Match-Up Result
 Thursday, March 12 Dynamo Kyiv at Everton 1-2
 Thursday, March 19  Everton at Dynamo Kyiv 2-5

 

Dnipro Dnipropetrovsk (UKR) vs. Ajax (NED) (Dnipro advances on away goals)

Date Match-Up Result
Thursday, March 12  Ajax at Dnipro Dnipropetrovsk 0-1
 Thursday, March 19   Dnipro Dnipropetrovsk at Ajax 1-2

 

Villarreal (ESP) vs. Sevilla (ESP) (Sevilla advances 5-2 on aggregate)

Date Match-Up Result
 Thursday, March 12 Sevilla at Villarreal 3-1
 Thursday, March 19  Villarreal at Sevilla 1-2